: In certain medical conditions like Resistance to Thyroid Hormone (RTH) syndrome, a mutation at this specific spot (R383) impairs the receptor's ability to release "corepressors".
: Normally, the RAR works with another protein (RXR) to bind to DNA. The R383 area is part of the machinery that ensures genes are only turned on when the proper signal (ligand) is present.
: Its unique reversed direction switch . Unlike most tools, turning the switch clockwise makes the screw go in clockwise, making it more intuitive for users.
(often stylized with a trailing 'R' or 'rar' in search terms) is a popular .