Oscars Guyfamily Guy : Season 21 Episode 1 May 2026

The episode originally aired on September 25, 2022. Notably, it contains , a departure from the show's usual format.

: A parody of the 1999 Best Picture winner featuring Kevin Spacey's character, Lester Burnham. Oscars GuyFamily Guy : Season 21 Episode 1

: Lois stars as rookie FBI agent Clarice Starling, who seeks help from an imprisoned Hannibal Lecter (Stewie) to track down the serial killer Buffalo Bill (Chris). The episode originally aired on September 25, 2022