[s5e22] What A Difference A Day Makes → «TOP»

: To promote the 100th episode, ABC created a real wedding website for Meredith and Derek that fans could actually visit and RSVP to.

: As a wedding gift, Derek gives Meredith her first solo surgery—a successful colon surgery overseen by Richard Webber. [S5E22] What a Difference a Day Makes

: After Derek and Bailey discover that Izzie has an inoperable brain tumor, the group decides to celebrate her life and love immediately. : To promote the 100th episode, ABC created

The episode's central plot twist occurs when Meredith and Derek decide to give their meticulously planned wedding to Izzie and Alex. : To promote the 100th episode

While the wedding takes center stage, the hospital remains in chaos due to a tragic car crash involving college students on their way to graduation.